సేలం చంద్రశేఖర్ కరోనా సోకడంతో చికిత్స పొందుతూ 2021, మే10న మరణించాడు.<ref name="Ghajini, Sullan producer Salem Chandrasekharan passes away due to COVID-19">{{cite news |last1=The New Indian Express |title=Ghajini, Sullan producer Salem Chandrasekharan passes away due to COVID-19 |url=https://www.cinemaexpress.com/stories/news/2021/may/10/ghajini-sullan-producer-salem-chandrasekharan-passes-away-due-to-covid-19-24423.html |accessdate=12 May 2021 |work=The New Indian Express |date=10 May 2021 |archiveurl=httphttps://web.archive.org/web/20210512042724/https://www.cinemaexpress.com/stories/news/2021/may/10/ghajini-sullan-producer-salem-chandrasekharan-passes-away-due-to-covid-19-24423.html |archivedate=12 Mayమే 2021 |url-status=live }}</ref><ref name="గజిని తమిళ నిర్మాత కన్నుమూత">{{cite news |last1=Sakshi |title=గజిని తమిళ నిర్మాత కన్నుమూత |url=https://www.sakshi.com/telugu-news/movies/ghajini-producer-passed-away-tamil-nadu-1363197 |accessdate=12 May 2021 |work=Sakshi |date=12 May 2021 |archiveurl=httphttps://web.archive.org/web/20210512042826/https://www.sakshi.com/telugu-news/movies/ghajini-producer-passed-away-tamil-nadu-1363197 |archivedate=12 Mayమే 2021 |language=te |url-status=live }}</ref><ref name="Salem Chandrasekharan passes away due to COVID-19 complications">{{cite news |last1=Republic World |first1= |title=Salem Chandrasekharan passes away due to COVID-19 complications |url=https://www.republicworld.com/entertainment-news/regional-indian-cinema/salem-chandrasekharan-passes-away-due-to-covid-19-complications.html |accessdate=12 May 2021 |date=12 May 2021 |archiveurl= |archivedate=12 May 2021}}</ref>
